Inhaltsbereich

• Modern electrophysiological techniques in vitro and in vivo
  Synaptic plasticity and intrinsic properties of neurons in pain pathways are studied in our lab by measuring extracellular field potentials in the intact animal and by performing whole-cell patch-clamp recordings from identified nociceptive neurons in spinal cord slices with long-dorsal roots attached. - more -

• State of the art live-cell imaging
  We perform widefield ratiometric Ca²⁺ imaging with Ca²⁺-sensitive dyes, as well as high-resolution confocal and multiphoton laser scanning microscopy in vitro and in vivo. - more -

• Behavioral testing and animal models
  Standard and clinically-relevant behavioural assays and models are used to assess different modalities of nociception and further the understanding of inflammation and neuropathic pain. The CBR is equipped with state of the art behavioral testing suites and sterile small animal surgery facilities.

• Immunohistochemical, biochemical and molecular biological techniques
  These standard techniques are used in our lab to detect cells, neurites,  synapses, subsynaptic structures, receptors, neuronal transmitters, phosphorylation sites etc. - more -