Center for Brain Research

2022 Original Articles
o	Westerhout EM, Hamdi M, Stroeken P, Nowakowska NE, Lakeman A, van Arkel J, Hasselt NE, Bleijlevens B, Akogul N, Haneveld F, Chan A, van Sluis P, Zwijnenburg D, Volckmann R, van Noesel CJ, Adameyko I, van Groningen T, Koster J, Valentijn LJ, van Nes J, Versteeg R. (2022) Mesenchymal type neuroblastoma cells escape ALK inhibitors Cancer Res, 82(3): 484-496
o	Rauschmeier R, Reinhardt A, Gustafsson C, Glaros V, Artemov AV, Dunst J, Taneja R, Adameyko I, Månsson R, Busslinger M, Kreslavsky T.exp (2022) Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis J Exp Med, 219(2): e20211406
o	Tesařová M, Mancini L, Mauri E, Aljančič G, Năpăruş-Aljančič M, Kostanjšek R, Bizjak Mali L, Zikmund T, Kaucká M, Papi F, Goyens J, Bouchnita A, Hellander A, Adameyko I, Kaiser J (2022) Living in darkness: Exploring adaptation of Proteus anguinus in 3 dimensions by X-ray imaging GigaScience, 11: giac030
o	Steinkellner H, Kempaiah P, Beribisky A, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam J, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F (2022) TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome Int J Biol Macromol, 209: 972-983
o	Frieser D, Pignata A, Khajavi L, Shlesinger D, Gonzalez-Fierro C, Nguyen X, Yermanos A, Merkler D, Höftberger R, Desestret V, Mair K, Bauer J, Masson F, Liblau R (2022) Tissue-resident CD8 ⁺ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons Sci Transl Med, 14 (640):
2022 Reviews
o	Lassmann H (2022) The Contribution of Neuropathology to Multiple Sclerosis Research Eur J Neurol, : Apr 15. doi: 10.1111/ene.15360. Online ahead of print.
o	Erickson A, Kameneva P, Adameyko I (2022) The transcriptional portraits of the neural crest at the individual cell level Semin Cell Dev Biol, : Mar 5;S1084-9521(22)00057-X. Online ahead of print.
o	Vanderdonckt P, Aloisi F, Comi G, de Bruyn A, Hartung H, Huitinga I, Kuhlmann T, Lucchinetti C, Metz I, Reynolds R, Lassmann H (2022) Tissue donations for multiple sclerosis research: current state and suggestions for improvement Brain Commun, 4 (2):
o	Lassmann H (2022) Tumefactive Multiple Sclerosis or Inflammatory Demyelinating Disease with Large Lesions? Eur J Neurol, 29(3): 687-688
2021 Original Articles
o	Häusler D, Akgün K, Stork L, Lassmann H, Ziemssen T, Brück W, Metz I. (2021) CNS inflammation after natalizumab therapy for multiple sclerosis: A retrospective histopathological and CSF cohort study Brain Pathol, 31(6): e12969
o	Zrzavy T, Schwaiger C, Wimmer I, Berger T, Bauer J, Butovsky O, Schwab J, Lassmann H, Höftberger R (2021) Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury Brain, 144(1): 144-161
o	Beltrán E+, Paunovic M+, Gebert D, Cesur E, Jeitler M, Höftberger R, Malotka J, Mader S, Kawakami N, Meinl E, Bradl M, Dornmair K, Lassmann H* + sharing co-first; sharing senior authorship (2021) Archeological neuroimmunology: resurrection of a pathogenic immune response from a historical case sheds light on human autoimmune encephalomyelitis and multiple sclerosis Acta Neuropathol*, 141(1): 67-83
o	Petersen MA, Tognatta R, Meyer-Franke A, Bushong EA, Mendiola AS, Yan Z, Muthusamy A, Merlini M, Meza-Acevedo R, Cabriga B, Zhou Y, Thomas R, Ryu JK, Lassmann H, Ellisman MH, Akassoglou K. (2021) BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis. Brain, 144(8): .2291-2301
o	Tobin W, Kalinowska-Lyszczarz A, Weigand S, Guo Y, Tosakulwong N, Parisi J, Metz I, Frischer J, Lassmann H, Brück W, Linbo L, Lucchinetti C (2021) Clinical Correlation of Multiple Sclerosis Immunopathologic Subtypes Neurology, 97(19): e1906-e1913
o	Kameneva P, V.Artemov A, Kastriti M, Sundström E, Kharchenko P, Adameyko I (2021) Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla Cancer Cell, Apr 27;S1535-6108(21)00217-8. : doi: 10.1016/j.ccell.2021.04.009.
o	Papazian I, Tsoukala E, Boutou A, Karamita M, Kambas K, Iliopoulou L, Fischer R, Kontermann R, Denis M, Kollias G, Lassmann H, Probert L (2021) Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice J Neuroinflammation, 18 (1): 222.
o	Hamminger P, Marchetti L, Preglej T, Platzer R, Zhu C, Kamnev A, Rica R, Stolz V, Sandner L, Alteneder M, Kaba E, Waltenberger D, Huppa J, Trauner M, Bock C, Lyck R, Bauer J, Dupré L, Seiser C, Boucheron N, Engelhardt B, Ellmeier W (2021) Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases J Autoimmun, 119: 102610
o	Wimmer I, Scharler C, Kadowaki T, Hillebrand S, Scheiber‐Mojdehkar B, Ueda S, Bradl M, Berger T, Lassmann H, Hametner S (2021) Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low‐grade haemolysis of fragile macrocytic red blood cells Brain Pathol, 31(2): 333-345 \| Weblink \|
o	Tham M, Frischer J, Weigand S, Fitz‐Gibbon P, Webb S, Guo Y, Adiele R, Robinson C, Brück W, Lassmann H, Furber K, Pushie M, Parisi J, Lucchinetti C, Popescu B (2021) Iron heterogeneity in early active multiple sclerosis lesions Ann Neurol, 89(3): 498-510
o	Dal-Bianco A, Schranzer R, Grabner G, Lanzinger M, Kolbrink S, Pusswald G, Altmann P, Ponleitner M, Weber M, Kornek B, Zebenholzer K, Schmied C, Berger T, Lassmann H, Trattnig S, Hametner S, Leutmezer F, Rommer P (2021) Iron Rims in Patients With Multiple Sclerosis as Neurodegenerative Marker? A 7-Tesla Magnetic Resonance Study Front Neurol, 12: 632749
o	Glaros V, Rauschmeier R, Artemov A, Reinhardt A, Ols S, Emmanouilidi A, Gustafsson C, You Y, Mirabello C, Björklund, Perez L, King N, Månsson R, Angeletti D, Loré K, Adameyko I, Busslinger M, Kreslavsky T (2021) Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response Immunity, 54 (9): 2005-2023.e10
o	Dal-Bianco A, Grabner G, Kronnerwetter C, Weber M, Kornek B, Kasprian G, Berger T, Leutmezer F, Rommer P, Trattnig S, Lassmann H, Hametner S (2021) Long-term evolution of multiple sclerosis iron rim lesions in 7 T MRI Brain, 144(3): 833-847
o	Doss P, Umair M, Baillargeon J, Fazazi R, Fudge N, Akbar I, Yeola A, Williams J, Leclercq M, Joly-Beauparlant C, Beauchemin P, Ruda G, Alpaugh M, Anderson A, Brennan P, Droit A, Lassmann H, Moore C, Rangachari M (2021) Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity Cell Rep, 34 (10): 108833
o	Metz I, Gavrilova R, Weigand S, Frischer J, Popescu B, Guo Y, Gloth M, Tobin W, Zalewski N, Lassmann H, Tillema J, Erickson B, Parisi J, Becker S, König F, Brück W, Lucchinetti C (2021) MRI Correlates of Multiple Sclerosis Immunopathological Patterns Ann Neurol, 90(3): 440-454
o	Marignier R, Hacohen Y, Cobo-Calvo A, Pröbstel A, Aktas O, Alexopoulos H, Amato M, Asgari N, Banwell B, Bennett J, Brilot F, Capobianco M, Chitnis T, Ciccarelli O, Deiva K, De Sèze J, Fujihara K, Jacob A, Kim H, Kleiter I, Lassmann H, Leite M, Linington C, Meinl E, Palace J, Paul F, Petzold A, Pittock S, Reindl M, Sato D, Selmaj K, Siva A, Stankoff B, Tintore M, Traboulsee A, Waters P, Waubant E, Weinshenker B, Derfuss T, Vukusic S, Hemmer B (2021) Myelin-oligodendrocyte glycoprotein antibody-associated disease Lancet Neurol, 20 (9): 762-772
o	Kaucka M, Szarowska B, Kavkova M, Kastriti M, Kameneva P, Schmidt I, Peskova L, Joven Araus A, Simon A, Kaiser J, Adameyko I (2021) Nerve-associated Schwann cell precursors contribute extracutaneous melanocytes to the heart, inner ear, supraorbital locations and brain meninges Cell Mol Life Sci, : 2021 Jul 18. doi: 10.1007/s00018-021-03885-9. Online ahead of print. PMID: 34274976
o	Zrzavy T, Endmayr V, Bauer J, Macher S, Mossaheb N, Schwaiger C, Ricken G, Winklehner M, Glatter S, Breu M, Wimmer I, Kovacs G, Risser D, Klupp N, Simonitsch‐Klupp I, Roetzer T, Rommer P, Berger T, Gelpi E, Lassmann H, Graus F, Dalmau J, Höftberger R (2021) Neuropathological variability within a spectrum of NMDAR‐encephalitis. Ann Neurol, : 2021 Sep 25. doi: 10.1002/ana.26223. Online ahead of print.
o	Förster M, Nelke C, Räuber S, Lassmann H, Ruck T, Sormani MP, Signori A, Hartung HP, Küry P, Meuth SG, Kremer D (2021) Nitrosative Stress Molecules in Multiple Sclerosis: A Meta-Analysis Biomedicines, 9(12): 1899
o	Cubas-Núñez L, Gil-Perotín S, Castillo-Villalba J, López V, Solís Tarazona L, Gasqué-Rubio R, Carratalá-Boscá S, Alcalá-Vicente C, Pérez-Miralles F, Lassmann H, Casanova B (2021) Potential Role of CHI3L1+ Astrocytes in Progression in MS Neurol Neuroimmunol Neuroinfl, 8 (3): e972
o	Aschauer C, Jelencsics K, Hu K, Heinzel A, Gregorich M, Vetter J, Schaller S, Winkler S, Weinberger J, Pimenov L, Gualdoni G, Eder M, Kainz A, Troescher A, Regele H, Reindl-Schwaighofer R, Wekerle T, Huppa J, Sykes M, Oberbauer R (2021) Prospective Tracking of Donor-Reactive T-Cell Clones in the Circulation and Rejecting Human Kidney Allografts Front Immunol, 12: 750005
o	Krivanek J, Lavicky J, Bouderlique T, Adameyko I (2021) Rapid Isolation of Single Cells from Mouse and Human Teeth J Vis Exp, (176):
o	Kamenev D, Sunadome K, Shirokov M, Chagin A, Singh A, Irion U, Adameyko I, Fried K, Dyachuk V (2021) Schwann cell precursors generate sympathoadrenal system during zebrafish development J Neurosci Res, : 99(10)
o	Kameneva P, Artemov A, Kastriti M, Faure L, Olsen T, Otte J, Erickson A, Semsch B, Andersson E, Ratz M, Frisén J, Tischler A, de Krijger R, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundström E, Mei S, Kogner P, Baryawno N, Kharchenko P, Adameyko I (2021) Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin Nature Genetics, : 53(5)
o	Bedoya-Reina O, Li W, Arceo M, Plescher M, Bullova P, Pui H, Kaucka M, Kharchenko P, Martinsson T, Holmberg J, Adameyko I, Deng Q, Larsson C, Juhlin C, Kogner P, Schlisio S (2021) Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors Nat Commun, 12 (1): 5309
o	Takai Y, Misu T, Suzuki H, Takahashi T, Okada H, Tanaka S, Okita K, Sasou S, Watanabe M, Namatame C, Matsumoto Y, Ono H, Kaneko K, Nishiyama S, Kuroda H, Nakashima I, Lassmann H, Fujihara K, Itoyama Y, Aoki M (2021) Staging of astrocytopathy and complement activation in neuromyelitis optica spectrum disorders Brain, 144: 2401-2415
o	Zhao J, Faure L, Adameyko I, Sharpe PT (2021) Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis Stem Cells, 39(1): 92-102
o	Tröscher A, Sakaraki E, Mair K, Köck U, Racz A, Borger V, Cloppenborg T, Becker A, Bien C, Bauer J (2021) T cell numbers correlate with neuronal loss rather than with seizure activity in medial temporal lobe epilepsy Epilepsia, 62 (6): 1343-1353
o	Rodríguez-Pascau L, Vilalta A, Cerrada M, Traver E, Forss-Petter S, Weinhofer I, Bauer J, Kemp S, Pina G, Pascual S, Meya U, Musolino P, Berger J, Martinell M, Pizcueta P (2021) The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy Sci Transl Med, 13 (596): eabc0555
o	Uçar M, Kamenev D, Sunadome K, Fachet D, Lallemend F, Adameyko I, Hadjab S, Hannezo E (2021) Theory of branching morphogenesis by local interactions and global guidance Nat Commun, 12 (1): 6830
o	Fleischer V, Gonzalez-Escamilla G, Ciolac D, Albrecht P, Küry P, Gruchot J, Dietrich M, Hecker C, Müntefering T, Bock S, Oshaghi M, Radetz A, Cerina M, Krämer J, Wachsmuth L, Faber C, Lassmann H, Ruck T, Meuth SG, Muthuraman M, Groppa S. (2021) Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans Proc Natl Acad Sci USA, 118(36): e2025000118
o	Colin A, Micali G, Faure L, Cosentino Lagomarsino M, van Teeffelen S (2021) Two different cell-cycle processes determine the timing of cell division in Escherichia coli eLife, 10: e67495
o	Matula J, Tesarova M, Zikmund T, Kaucka M, Adameyko I, Kaiser J (2021) X-ray microtomography–based atlas of mouse cranial development GigaScience, 10 (3):
2021 Reviews
o	Schwabenland M, Brück W, Priller J, Stadelmann C, Lassmann H, Prinz M (2021) Analyzing microglial phenotypes across neuropathologies: a practical guide Acta Neuropathol, 142(6): 923-936.
o	Baert L, Marignier R, Lassmann H, Huard B (2021) Case Report: In Situ Expression of a Proliferation-Inducing Ligand in Neuromyelitis Optica Front Neurol, 12: e721877
o	Wiendl H, Gross C, Bauer J, Merkler D, Prat A, Liblau R (2021) Fundamental mechanistic insights from rare but paradigmatic neuroimmunological diseases Nat Rev Neurol, 17 (7): 433-447
o	Dal-Bianco A, Höftberger R, Lassmann H, Berger T (2021) Kurt Jellinger 90: his contribution to neuroimmunology J Neural Transm, 128(10): 1545-1550
o	Kameneva P, Kastriti M, Adameyko I (2021) Neuronal lineages derived from the nerve-associated Schwann cell precursors Cell Mol Life Sci, 78(2): 513-529
o	Cree B, Arnold D, Chataway J, Chitnis T, Fox R, Ramajo A, Murphy N, Lassmann H (2021) Secondary Progressive Multiple Sclerosis: New Insights Neurology, 97(8): 378-388
o	Comi G, Bar‐Or A, Lassmann H, Uccelli A, Hartung H, Montalban X, Sørensen P, Hohlfeld R, Hauser S, Absinta M, Battistini L, Bennet J, Bergman J, Calabrese M, Correale J, Dornmair K, Moiola L, Edan G, Fujihara K, Gastaldi M, Ghezzi A, Gommerman J, Hausler D, Hoftberger R, Kappos L, Sörensen P, Klotz L, Leocani L, Magliozzi R, Michel L, Meinl E, Misu T, Palace J, Prat A, Rocca M, Selmaj K, (2021) The role of B cells in Multiple Sclerosis and related disorders Ann Neurol, 89(1): 13-23
2021 Book Chapters
o	Lassmann, Hans (2021) Pathophysiological Bases of Autoimmune-Initiated/Mediated Neurodegeneration. In: Sergiu Groppa and Sven G. Meuth: (Eds.), Translational Methods for Multiple Sclerosis Research Springer Nature, Cham Switzerland: 3-12
2020 Original Articles
o	Kuehn J, Scheuerle A, Bauer J, Becker A, Wirtz R, Lewerenz J (2020) A 64‐Year‐Old Patient With a Mesiotemporal Mass and Symptomatic Epilepsy Brain Pathol, 30 (2): 413-414
o	Klinger M, Zugmaier G, Nägele V, Goebeler M, Brandl C, Stelljes M, Lassmann H, von Stackelberg A, Bargou R, Kufer P (2020) Adhesion of T cells to endothelial cells facilitates blinatumomab-associated neurologic adverse events Cancer Res, 80 (1) : 91-101
o	Sierra R, Gómez Bustillo S, Kameneva P, Fiore E, Mazzone G, Borda M, Blanco M, Usuardi C, Furlan A, Ernfors P, Alaniz L, Montaner A, Adameyko I, Aquino J (2020) Contribution of neural crest and GLAST + Wnt1 + bone marrow pericytes with liver fibrogenesis and/or regeneration Liver Int, 40 (4): 977-987
o	Zhang Y, Kameneva P, Annusver K, Kasper M, Chagin A, Adameyko I, Xie M (2020) Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds Dev Dyn, 249(6): 711-722
o	Krivanek J, Soldatov R, Kastriti M, Chontorotzea T, Herdina A, Petersen J, Szarowska B, Landova M, Matejova V, Holla L, Kuchler U, Zdrilic I, Vijaykumar A, Balic A, Marangoni P, Klein O, Neves V, Yianni V, Sharpe P, Harkany T, Metscher B, Bajénoff M, Mina M, Fried K, Kharchenko P, Adameyko I (2020) Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth Nat Commun, 11 (1): 4816
o	Licht-Mayer S, Campbell G, Canizares M, Mehta A, Gane A, McGill K, Ghosh A, Fullerton A, Menezes N, Dean J, Dunham J, Al-Azki S, Pryce G, Zandee S, Zhao C, Kipp M, Smith K, Baker D, Altmann D, Anderton S, Kap Y, Laman J, Hart B, Rodriguez M, Watzlawick R, Schwab J, Carter R, Morton N, Zagnoni M, Franklin R, Mitchell R, Fleetwood-Walker S, Lyons D, Chandran S, Lassmann H, Trapp B, Mahad D (2020) Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis Acta Neuropathol, 140(2): 143-167
o	Zhang Y, Annusver K, Sunadome K, Kameneva P, Edwards S, Lei G, Kasper M, Chagin A, Adameyko I, Xie M (2020) Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis Front Cell Dev Biol, 8: 22
o	Tsymala I, Nigritinou M, Zeka B, Schulz R, Niederschick F, Matković M, Bauer I, Szalay M, Schanda K, Lerch M, Misu T, Fujihara K, Bennett J, Dahle C, Pache F, Rommer P, Leutmezer F, Illes Z, Leite M, Palace J, Scholze P, Reindl M, Lassmann H, Bradl M (2020) Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes Acta Neuropathologica Communications, 15; 8 (1): \| Supplement \|
o	Eggers C, Kopatz V, Dörr W, Lassmann H, Geinitz H (2020) Localised multiple sclerosis-like disease after irradiation of the cervicothoracic spinal cord Mult Scler Relat Disord., 45: 102443
o	Dagkonaki A, Avloniti M, Evangelidou M, Papazian I, Kanistras I, Tseveleki V, Lampros F, Tselios T, Jensen L, Möbius W, Ruhwedel T, Androutsou M, Matsoukas J, Anagnostouli M, Lassmann H, Probert L (2020) Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions Front Immunol, 11: 575451
o	Romanov R, Tretiakov E, Kastriti M, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews W, Parnavelas J, Farlik M, Bock C, Adameyko I, Hökfelt T, Keimpema E, Harkany T (2020) Molecular design of hypothalamus development Nature, 582(7811): 246-252
o	Takai Y, Misu T, Kaneko K, Chihara N, Narikawa K, Tsuchida S, Nishida H, Komori T, Seki M, Komatsu T, Nakamagoe K, Ikeda T, Yoshida M, Takahashi T, Ono H, Nishiyama S, Kuroda H, Nakashima I, Suzuki H, Bradl M, Lassmann H, Fujihara K, Aoki M; Japan MOG-antibody Disease Consortium. (2020) Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study Brain, 143(5):: 1431-1446
o	Gerhards R, Pfeffer L, Lorenz J, Starost L, Nowack L, Thaler F, Schlüter M, Rübsamen H, Macrini C, Winklmeier S, Mader S, Bronge M, Grönlund H, Feederle R, Hsia H, Lichtenthaler S, Merl-Pham J, Hauck S, Kuhlmann T, Bauer I, Beltran E, Gerdes L, Mezydlo A, Bar-Or A, Banwell B, Khademi M, Olsson T, Hohlfeld R, Lassmann H, Kümpfel T, Kawakami N, Meinl E (2020) Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS Acta Neuropathologica Communications, 8 (1): 207
o	Gödel C, Kunkel B, Kashani A, Lassmann H, Arumugam M, Krishnamoorthy G (2020) Perturbation of gut microbiota decreases susceptibility but does not modulate ongoing autoimmune neurological disease J Neuroinflammation, 17 (1): 79
o	Klimovich A, Giacomello S, Björklund A, Faure L, Kaucka M, Giez C, Murillo-Rincon A, Matt A, Willoweit-Ohl D, Crupi G, de Anda J, Wong G, D’Amato M, Adameyko I, Bosch T (2020) Prototypical pacemaker neurons interact with the resident microbiota Proc Natl Acad Sci USA, 117(30): 17854-17863
o	Albergante L, Mirkes E, Bac J, Chen H, Martin A, Faure L, Barillot E, Pinello L, Gorban A, Zinovyev A (2020) Robust and Scalable Learning of Complex Intrinsic Dataset Geometry via ElPiGraph Entropy, 22 (3): 296
o	Xie M, Gol'din P, Herdina AN, Estefa J, Medvedeva EV, Li L, Newton PT, Kotova S, Shavkuta B, Saxena A, Shumate LT, Metscher BD, Großschmidt K, Nishimori S, Akovantseva A, Usanova AP, Kurenkova AD, Kumar A, Arregui IL, Tafforeau P, Fried K, Carlström M, Simon A, Gasser C, Kronenberg HM, Bastepe M, Cooper KL, Timashev P, Sanchez S, Adameyko I, Eriksson A, Chagin AS. (2020) Secondary ossification center induces and protects growth plate structure eLife, 9: e55212
o	Faure L, Wang Y, Kastriti M, Fontanet P, Cheung K, Petitpré C, Wu H, Sun L, Runge K, Croci L, Landy M, Lai H, Consalez G, de Chevigny A, Lallemend F, Adameyko I, Hadjab S (2020) Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates Nat Commun, 11 (1): 4175
o	Höftberger R, Guo Y, Flanagan E, Lopez-Chiriboga A, Endmayr V, Hochmeister S, Joldic D, Pittock S, Tillema J, Gorman M, Lassmann H, Lucchinetti C (2020) The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody Acta Neuropathol, 139(5): 875-892
o	Malviya M, Saoudi A, Bauer J, Fillatreau S, Liblau R (2020) Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells J Autoimmun, 108: 102401
o	Zierfuss B, Weinhofer I, Kühl J, Köhler W, Bley A, Zauner K, Binder J, Martinović K, Seiser C, Hertzberg C, Kemp S, Egger G, Leitner G, Bauer J, Wiesinger C, Kunze M, Forss-Petter S, Berger J (2020) Vorinostat in the acute neuroinflammatory form of X-linked adrenoleukodystrophy Ann Clin Transl Neurol, 7 (5): 639-652
2020 Reviews
o	Filippi M, Preziosa P, Langdon D, Lassmann H, Paul F, Rovira A, Schoonheim M, Solari A, Stankoff B, Rocca M (2020) Identifying Progression In Multiple Sclerosis: New Perspectives Ann Neurol, 88(3): 438-452
o	Absinta M, Lassmann H, Trapp B (2020) Mechanisms underlying progression in multiple sclerosis Curr Opin Neurol, 33(3): 277-285.
o	Lassmann H (2020) Pathology of inflammatory diseases of the nervous system: Human disease versus animal models Glia, 68 (4): 830-844
o	Kastriti M, Kameneva P, Adameyko I (2020) Stem cells, evolutionary aspects and pathology of the adrenal medulla: A new developmental paradigm Mol Cell Endocrinol, 518: 110998
2020 Book Chapters
o	Höftberger R, Lassmann H (2020) Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalomyelitis. In: Fabrice Chretien (Eds.), Infections of the Central Nervous System: Pathology and Genetics John Wiley & Sons, Inc; Oxford, UK, Hoboken, USA: 251-257
o	Adameyko, I (2020) Elaboration of Fates in Neural Crest Lineage. In: Brian F. Eames, Daniel Meulemans Medeiros and Igor Adameyko (Eds.), Evolving Neural Crest Cells; CRC Press - Taylor & Francis Group, Boca Raton, London, New York : 157-183
o	Adameyko, I and Eames, BF (2020) Evolving Neural Crest Cells: Hopes for Present and Future Understanding. In: Brian F. Eames, Daniel Meulemans Medeiros and Igor Adameyko (Eds.), Evolving Neural Crest Cells; CRC Press - Taylor & Francis Group, Boca Raton, London, New York : 265-274
2019 Original Articles
o	Heckova E, Strasser B, Hangel G, Považan M, Dal-Bianco A, Rommer P, Bednarik P, Gruber S, Leutmezer F, Lassmann H, Trattnig S, Bogner W (2019) 7 T Magnetic Resonance Spectroscopic Imaging in Multiple Sclerosis Invest Radiol, 54(4): 247-254
o	Newton P, Li L, Zhou B, Schweingruber C, Hovorakova M, Xie M, Sun X, Sandhow L, Artemov A, Ivashkin E, Suter S, Dyachuk V, El Shahawy M, Gritli-Linde A, Bouderlique T, Petersen J, Mollbrink A, Lundeberg J, Enikolopov G, Qian H, Fried K, Kasper M, Hedlund E, Adameyko I, Sävendahl L, Chagin A (2019) A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate Nature, 567 (7747): 234-238
o	Baert L, Benkhoucha M, Popa N, Ahmed M, Manfroi B, Boutonnat J, Sturm N, Raguenez G, Tessier M, Casez O, Marignier R, Ahmadi M, Broisat A, Ghezzi C, Rivat C, Sonrier C, Hahne M, Baeten D, Vives R, Lortat-Jacob H, Marche P, Schneider P, Lassmann H, Boucraut J, Lalive P, Huard B (2019) APRIL-mediated anti-inflammatory response of astrocytes in multiple sclerosis Ann Neurol, 85(3): 406-420
o	Gross C, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher A, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud D, Loussouarn D, Parratt J, Barnett M, Buckland M, Hardy T, Reddel S, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth S, Martin-Blondel G, Wiendl H, Liblau R (2019) CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome Nat Commun, 10 (1): 5779
o	Hillebrand S, Schanda K, Nigritinou M, Tsymala I, Böhm D, Peschl P, Takai Y, Fujihara K, Nakashima I, Misu T, Reindl M, Lassmann H, Bradl M (2019) Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat Acta Neuropathol, 137(3): 467-485
o	Konjevic Sabolek M, Held K, Beltrán E, Niedl A, Meinl E, Hohlfeld R, Lassmann H, Dornmair K (2019) Communication of CD 8 + T cells with mononuclear phagocytes in multiple sclerosis Ann Clin Transl Neurol, 6(7): 1151-1164
o	Yshii L, Pignolet B, Mauré E, Pierau M, Brunner-Weinzierl M, Hartley O, Bauer J, Liblau R (2019) IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration JCI Insight, 4 (7):
o	Hernández-Torres E, Wiggermann V, Machan L, Sadovnick A, Li D, Traboulsee A, Hametner S, Rauscher A (2019) Increased mean R2* in the deep gray matter of multiple sclerosis patients: Have we been measuring atrophy? J Magn Reson Imaging, 50 (1): 201-208
o	Magliozzi R, Hametner S, Facchiano F, Marastoni D, Rossi S, Castellaro M, Poli A, Lattanzi F, Visconti A, Nicholas R, Reynolds R, Monaco S, Lassmann H, Calabrese M (2019) Iron homeostasis, complement, and coagulation cascade as CSF signature of cortical lesions in early multiple sclerosis Ann Clin Transl Neurol, 6(11): 2150-2163
o	Bergner C, Meer F, Winkler A, Wrzos C, Türkmen M, Valizada E, Fitzner D, Hametner S, Hartmann C, Pfeifenbring S, Stoltenburg‐Didinger G, Brück W, Nessler S, Stadelmann C (2019) Microglia damage precedes major myelin breakdown in X‐linked adrenoleukodystrophy and metachromatic leukodystrophy Glia, 67 (6): 1196-1209
o	Wimmer I, Scharler C, Zrzavy T, Kadowaki T, Mödlagl V, Rojc K, Tröscher A, Kitic M, Ueda S, Bradl M, Lassmann H (2019) Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis Acta Neuropathologica Communications, 7 (1): 14 \| Weblink \|
o	Tröscher A, Wimmer I, Quemada-Garrido L, Köck U, Gessl D, Verberk S, Martin B, Lassmann H, Bien C, Bauer J (2019) Microglial nodules provide the environment for pathogenic T cells in human encephalitis Acta Neuropathol, 137(4): 137(4):619-635
o	Kau T, Hametner S, Endmayr V, Deistung A, Prihoda M, Haimburger E, Menard C, Haider T, Höftberger R, Robinson S, Reichenbach J, Lassmann H, Traxler H, Trattnig S, Grabner G (2019) Microvessels may Confound the “Swallow Tail Sign” in Normal Aged Midbrains: A Postmortem 7 T SW-MRI Study J Neuroimaging, 29(1): 65-69
o	Bernard-Valnet R, Cobo-Calvo A, Siegfried A, Marasescu R, Bonnan M, Ballan G, Ellie E, Bauer J, Uro-Coste E, Marignier R, Brassat D (2019) Paraneoplastic neuromyelitis optica and ovarian teratoma: A case series Mult Scler Relat Disord., 31: 97-100
o	Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller W, Lassmann H, Engelhardt B (2019) PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation Front Immunol, 10: 711 \| Weblink \|
o	Zrzavy T, Höftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, Lassmann H (2019) Pro-inflammatory Activation of Microglia in the Brain of Patients with Sepsis Neuropathol Appl Neurobiol, 45(3): 278-290
o	Prakash V, Carson B, Feenstra J, Dass R, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks M, Kurylo C, Batchelder J, Haller K, Hashimoto A, Rundqivst H, Condeelis J, Allis C, Drygin D, Nieto M, Andäng M, Percipalle P, Bergh J, Adameyko I, Farrants A, Hartman J, Lyden D, Pietras K, Blanchard S, Vincent C (2019) Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease Nat Commun, 10 (1):
o	Anaby D, Morozov D, Seroussi I, Hametner S, Sochen N, Cohen Y (2019) Single‐ and double‐Diffusion encoding MRI for studying ex vivo apparent axon diameter distribution in spinal cord white matter NMR Biomed, 32 (12): e4170
o	Soldatov R, Kaucka M, Kastriti M, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino M, Boismoreau F, Hilscher M, Yokota C, Qian X, Nilsson M, Bronner M, Croci L, Hsiao W, Guertin D, Brunet J, Consalez G, Ernfors P, Fried K, Kharchenko P, Adameyko I (2019) Spatiotemporal structure of cell fate decisions in murine neural crest Science, 364 (6444): eaas9536
o	Haindl M, Köck U, Zeitelhofer-Adzemovic M, Fazekas F, Hochmeister S (2019) The formation of a glial scar does not prohibit remyelination in an animal model of multiple sclerosis Glia, 67 (3): 467-481
2019 Reviews
o	Lassmann H (2019) Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis Front Immunol, 9: 3116
o	Titulaer M, Irani S, Lassmann H (2019) PDE10A antibodies in autoimmune encephalitis Neurology, 93(8): 327-328
o	Ciccarelli O, Cohen J, Reingold S, Weinshenker B, Amato M, Banwell B, Barkhof F, Bebo B, Becher B, Bethoux F, Brandt A, Brownlee W, Calabresi P, Chatway J, Chien C, Chitnis T, Ciccarelli O, Cohen J, Comi G, Correale J, De Sèze J, De Stefano N, Fazekas F, Flanagan E, Freedman M, Fujihara K, Galetta S, Goldman M, Greenberg B, Hartung H, Hemmer B, Henning A, Izbudak I, Kappos L, Lassmann H, Laule C, Levy M, Lublin F, Lucchinetti C, Lukas C, Marrie R, Miller A, Miller D, Montalban X, Mowry E, Ourselin S, Paul F, Pelletier D, Ranjeva J, Reich D, Reingold S, Rocca M, Rovira A, Schlaerger R, Soelberg Sorensen P, Sormani M, Stuve O, Thompson A, Tintoré M, Traboulsee A, Trapp B, Trojano M, Uitdehaag B, Vukusic S, Waubant E, Weinshenker B, Wheeler-Kingshott C, Xu J (2019) Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders Lancet Neurol, 18 (2): 185-197
o	Lassmann H (2019) The changing concepts in the neuropathology of acquired demyelinating central nervous system disorders. Curr Opin Neurol, 32(3): 313-319
o	Zrzavy T, Kollaritsch H, Rommer P, Boxberger N, Loebermann M, Wimmer I, Winkelmann A, Zettl U (2019) Vaccination in Multiple Sclerosis: Friend or Foe? Front Immunol, 10:
2018 Original Articles
o	Rubino S, Mayo L, Wimmer I, Siedler V, Brunner F, Hametner S, Madi A, Lanser A, Moreira T, Donnelly D, Cox L, Rezende R, Butovsky O, Lassmann H, Weiner H (2018) Acute microglia ablation induces neurodegeneration in the somatosensory system Nat Commun, 9 (1): 4578
o	Zrzavy T, Machado-Santos J, Christine S, Baumgartner C, Weiner H, Butovsky O, Lassmann H (2018) Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts Brain Pathol, 28(6): 791-805
o	Martin N, Molnar V, Szilagyi G, Elkjaer M, Nawrocki A, Okarmus J, Wlodarczyk A, Thygesen E, Palkovits M, Gallyas F, Larsen M, Lassmann H, Benedikz E, Owens T, Svenningsen A, Illes Z (2018) Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice Front Immunol, 9: 490
o	Weinhofer I, Zierfuss B, Hametner S, Wagner M, Popitsch N, Machacek C, Bartolini B, Zlabinger G, Ohradanova-Repic A, Stockinger H, Köhler W, Höftberger R, Regelsberger G, Forss-Petter S, Lassmann H, Berger J (2018) Impaired plasticity of macrophages in X-linked adrenoleukodystrophy Brain, 141: 2329-2342 \| Article (PDF) \|
o	Schweser F, Raffaini Duarte Martins A, Hagemeier J, Lin F, Hanspach J, Weinstock-Guttman B, Hametner S, Bergsland N, Dwyer M, Zivadinov R (2018) Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality Neuroimage, 167: 438-452
o	Blaabjerg M, Hemdrup A, Drici L, Ruprecht K, Garred P, Höftberger R, Kristensen B, Kondziella D, Sejbaek T, Hansen S, Nielsen H, Jensen P, Meyer M, Paul F, Lassmann H, Larsen M, Illes Z (2018) Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) Front Immunol, 9: 741
o	Martin N, Nawrocki A, Molnar V, Elkjaer M, Thygesen E, Palkovits M, Acs P, Sejbaek T, Nielsen H, Hegedus Z, Sellebjerg F, Molnar T, Barbosa E, Alcaraz N, Gallyas F, Svenningsen A, Baumbach J, Lassmann H, Larsen M, Illes Z (2018) Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes PlosOne, 13 (8): e0202530
o	Spadaro M, Winklmeier S, Beltrán E, Macrini C, Höftberger R, Schuh E, Thaler F, Gerdes L, Laurent S, Gerhards R, Brändle S, Dornmair K, Breithaupt C, Krumbholz M, Moser M, Kirshnamoorthy G, Kamp F, Jenne D, Hohlfeld R, Kümpfel T, Lassmann H, Kawakami N, Meinl E (2018) Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein Ann Neurol, 84(2): 315-328
o	Bagnato F, Hametner S, Franco G, Pawate S, Sriram S, Lassmann H, Gore J, Smith S, Dortch R (2018) Selective Inversion Recovery Quantitative Magnetization Transfer Brain MRI at 7T: Clinical and Postmortem Validation in Multiple Sclerosis J Neuroimaging, 28(4) : 380-388
o	Wimmer I, Tröscher A, Brunner F, Rubino S, Bien C, Weiner H, Lassmann H, Bauer J (2018) Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples Sci Rep, 8 (1): 6351 \| Weblink \|
o	Kap Y, Bus-Spoor C, van Driel N, Dubbelaar M, Grit C, Kooistra S, Fagrouch Z, Verschoor E, Bauer J, Eggen B, Harmsen H, Laman J, ’t Hart B (2018) Targeted Diet Modification Reduces Multiple Sclerosis–like Disease in Adult Marmoset Monkeys from an Outbred Colony J Immunol, 201 (11): 3229-3243
o	Machado-Santos J, Saji E, Tröscher A, Paunovic M, Liblau R, Gabriely G, Bien C, Bauer J, Lassmann H (2018) The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells Brain, 141(7): 2066-2082
o	Hametner S, Endmayr V, Deistung A, Palmrich P, Prihoda M, Haimburger E, Menard C, Feng X, Haider T, Leisser M, Köck U, Kaider A, Höftberger R, Robinson S, Reichenbach JR, Lassmann H, Traxler H, Trattnig S, Grabner G. (2018) The influence of brain iron and myelin on magnetic susceptibility and effective transverse relaxation - A biochemical and histological validation study Neuroimage, 179: 117-133.
o	Reinthaler E, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill C, Hoffjan S, Epplen J, Zettl U, Hecker M, Deutschländer A, Meuth S, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick A, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A (2018) TPP2 mutation associated with sterile brain inflammation mimicking MS Neurol Genet, 4 (6): e285
o	Lemke A, Ferguson J, Gross K, Penzenstadler C, Bradl M, Mayer R, Gerner C, Redl H, Wolbank S (2018) Transplantation of human amnion prevents recurring adhesions and ameliorates fibrosis in a rat model of sciatic nerve scarring Acta Biomater, 66: 335–349
o	Bagnato F, Hametner S, Boyd E, Endmayr V, Shi Y, Ikonomidou V, Chen G, Pawate S, Lassmann H, Smith S, Welch E (2018) Untangling the R2* contrast in multiple sclerosis: A combined MRI-histology study at 7.0 Tesla PlosOne, 13 (3): e0193839
2018 Reviews
o	Hametner S, Bianco AD, Trattnig S, Lassmann H. (2018) Iron related changes in MS lesions and their validity to characterize MS lesion types and dynamics with Ultra-high field magnetic resonance imaging Brain Pathol, 28(5): 743-749
o	Bradl M, Reindl M, Lassmann H (2018) Mechanisms for lesion localization in neuromyelitis optica spectrum disorders Curr Opin Neurol, 31(3): 325-333
o	O’Loughlin E, Madore C, Lassmann H, Butovsky O (2018) Microglial Phenotypes and Functions in Multiple Sclerosis Cold Spring Harb Perspect Med., 8 (2): a028993
o	Lassmann H (2018) Multiple Sclerosis Pathology Cold Spring Harb Perspect Med., 8(3): a028936
o	Lassmann H (2018) Multiple Sclerosis Pathology and its Reflection by Imaging Technologies: Introduction Brain Pathol, 28 (5): 721-722
o	Wimmer I, Zrzavy T, Lassmann H (2018) Neuroinflammatory responses in experimental and human stroke lesions J Neuroimmunol, 323: 10-18