Center for Brain Research

2020 Original Articles
o	Kuehn J, Scheuerle A, Bauer J, Becker A, Wirtz R, Lewerenz J (2020) A 64‐Year‐Old Patient With a Mesiotemporal Mass and Symptomatic Epilepsy Brain Pathol, 30 (2): 413-414
o	Klinger M, Zugmaier G, Nägele V, Goebeler M, Brandl C, Stelljes M, Lassmann H, von Stackelberg A, Bargou R, Kufer P (2020) Adhesion of T cells to endothelial cells facilitates blinatumomab-associated neurologic adverse events Cancer Res, 80 (1) : 91-101
o	Sierra R, Gómez Bustillo S, Kameneva P, Fiore E, Mazzone G, Borda M, Blanco M, Usuardi C, Furlan A, Ernfors P, Alaniz L, Montaner A, Adameyko I, Aquino J (2020) Contribution of neural crest and GLAST + Wnt1 + bone marrow pericytes with liver fibrogenesis and/or regeneration Liver Int, 40 (4): 977-987
o	Zhang Y, Kameneva P, Annusver K, Kasper M, Chagin A, Adameyko I, Xie M (2020) Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds Dev Dyn, 249(6): 711-722
o	Krivanek J, Soldatov R, Kastriti M, Chontorotzea T, Herdina A, Petersen J, Szarowska B, Landova M, Matejova V, Holla L, Kuchler U, Zdrilic I, Vijaykumar A, Balic A, Marangoni P, Klein O, Neves V, Yianni V, Sharpe P, Harkany T, Metscher B, Bajénoff M, Mina M, Fried K, Kharchenko P, Adameyko I (2020) Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth Nat Commun, 11 (1): 4816
o	Licht-Mayer S, Campbell G, Canizares M, Mehta A, Gane A, McGill K, Ghosh A, Fullerton A, Menezes N, Dean J, Dunham J, Al-Azki S, Pryce G, Zandee S, Zhao C, Kipp M, Smith K, Baker D, Altmann D, Anderton S, Kap Y, Laman J, Hart B, Rodriguez M, Watzlawick R, Schwab J, Carter R, Morton N, Zagnoni M, Franklin R, Mitchell R, Fleetwood-Walker S, Lyons D, Chandran S, Lassmann H, Trapp B, Mahad D (2020) Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis Acta Neuropathol, 140(2): 143-167
o	Zhang Y, Annusver K, Sunadome K, Kameneva P, Edwards S, Lei G, Kasper M, Chagin A, Adameyko I, Xie M (2020) Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis Front Cell Dev Biol, 8:
o	Tsymala I, Nigritinou M, Zeka B, Schulz R, Niederschick F, Matković M, Bauer I, Szalay M, Schanda K, Lerch M, Misu T, Fujihara K, Bennett J, Dahle C, Pache F, Rommer P, Leutmezer F, Illes Z, Leite M, Palace J, Scholze P, Reindl M, Lassmann H, Bradl M (2020) Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes Acta Neuropathologica Communications, 15; 8 (1): \| Supplement \|
o	Eggers C, Kopatz V, Dörr W, Lassmann H, Geinitz H (2020) Localised multiple sclerosis-like disease after irradiation of the cervicothoracic spinal cord Mult Scler Relat Disord., 45: 102443
o	Romanov R, Tretiakov E, Kastriti M, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews W, Parnavelas J, Farlik M, Bock C, Adameyko I, Hökfelt T, Keimpema E, Harkany T (2020) Molecular design of hypothalamus development Nature, : 2020 May 6. doi: 10.1038/s41586-020-2266-0. Online ahead of print
o	Takai Y, Misu T, Kaneko K, Chihara N, Narikawa K, Tsuchida S, Nishida H, Komori T, Seki M, Komatsu T, Nakamagoe K, Ikeda T, Yoshida M, Takahashi T, Ono H, Nishiyama S, Kuroda H, Nakashima I, Suzuki H, Bradl M, Lassmann H, Fujihara K, Aoki M; Japan MOG-antibody Disease Consortium. (2020) OUP accepted manuscript Brain, : May 15. pii: awaa102. doi: 10.1093/brain/awaa102. [Epub ahead of print]
o	Gödel C, Kunkel B, Kashani A, Lassmann H, Arumugam M, Krishnamoorthy G (2020) Perturbation of gut microbiota decreases susceptibility but does not modulate ongoing autoimmune neurological disease J Neuroinflammation, 17 (1): 79
o	Klimovich A, Giacomello S, Björklund �, Faure L, Kaucka M, Giez C, Murillo-Rincon A, Matt A, Willoweit-Ohl D, Crupi G, de Anda J, Wong G, D’Amato M, Adameyko I, Bosch T (2020) Prototypical pacemaker neurons interact with the resident microbiota PNAS, : 2020 Jul 9;201920469. doi: 10.1073/pnas.1920469117. Online ahead of print.
o	Faure L, Wang Y, Kastriti M, Fontanet P, Cheung K, Petitpré C, Wu H, Sun L, Runge K, Croci L, Landy M, Lai H, Consalez G, de Chevigny A, Lallemend F, Adameyko I, Hadjab S (2020) Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates Nat Commun, 11 (1): 4175
o	Höftberger R, Guo Y, Flanagan E, Lopez-Chiriboga A, Endmayr V, Hochmeister S, Joldic D, Pittock S, Tillema J, Gorman M, Lassmann H, Lucchinetti C (2020) The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody Acta Neuropathol, 139(5): 875-892
o	Malviya M, Saoudi A, Bauer J, Fillatreau S, Liblau R (2020) Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells J Autoimmun, 108: 102401
o	Zierfuss B, Weinhofer I, Kühl J, Köhler W, Bley A, Zauner K, Binder J, Martinović K, Seiser C, Hertzberg C, Kemp S, Egger G, Leitner G, Bauer J, Wiesinger C, Kunze M, Forss-Petter S, Berger J (2020) Vorinostat in the acute neuroinflammatory form of X-linked adrenoleukodystrophy Ann Clin Transl Neurol, 7 (5): 639-652
2020 Reviews
o	Filippi M, Preziosa P, Langdon D, Lassmann H, Paul F, Rovira �, Schoonheim M, Solari A, Stankoff B, Rocca M (2020) Identifying Progression In Multiple Sclerosis: New Perspectives Ann Neurol, : 2020 Jun 7. doi: 10.1002/ana.25808. Online ahead of print
o	Absinta M, Lassmann H, Trapp B (2020) Mechanisms underlying progression in multiple sclerosis Curr Opin Neurol, 33(3): 277-285.
o	Kameneva P, Kastriti M, Adameyko I (2020) Neuronal lineages derived from the nerve-associated Schwann cell precursors Cell Mol Life Sci, : Aug 3. doi: 10.1007/s00018-020-03609-5. Online ahead of print
o	Lassmann H (2020) Pathology of inflammatory diseases of the nervous system: Human disease versus animal models Glia, 68 (4): 830-844
o	Kastriti M, Kameneva P, Adameyko I (2020) Stem cells, evolutionary aspects and pathology of the adrenal medulla: A new developmental paradigm Mol Cell Endocrinol, Aug 17;110998. doi: 10.1016/j.mce.2020.110998. Online ahead of print. : 110998
2020 Book Chapters
o	Höftberger R, Lassmann H (2020) Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalomyelitis. In: Fabrice Chretien (Eds.), Infections of the Central Nervous System: Pathology and Genetics John Wiley & Sons, Inc; Oxford, UK, Hoboken, USA: 251-257
o	Adameyko, I (2020) Elaboration of Fates in Neural Crest Lineage. In: Brian F. Eames, Daniel Meulemans Medeiros and Igor Adameyko (Eds.), Evolving Neural Crest Cells; CRC Press - Taylor & Francis Group, Boca Raton, London, New York : 157-183
o	Adameyko, I and Eames, BF (2020) Evolving Neural Crest Cells: Hopes for Present and Future Understanding. In: Brian F. Eames, Daniel Meulemans Medeiros and Igor Adameyko (Eds.), Evolving Neural Crest Cells; CRC Press - Taylor & Francis Group, Boca Raton, London, New York : 265-274
2019 Original Articles
o	Heckova E, Strasser B, Hangel G, Považan M, Dal-Bianco A, Rommer P, Bednarik P, Gruber S, Leutmezer F, Lassmann H, Trattnig S, Bogner W (2019) 7 T Magnetic Resonance Spectroscopic Imaging in Multiple Sclerosis Invest Radiol, 54(4): 247-254
o	Newton P, Li L, Zhou B, Schweingruber C, Hovorakova M, Xie M, Sun X, Sandhow L, Artemov A, Ivashkin E, Suter S, Dyachuk V, El Shahawy M, Gritli-Linde A, Bouderlique T, Petersen J, Mollbrink A, Lundeberg J, Enikolopov G, Qian H, Fried K, Kasper M, Hedlund E, Adameyko I, Sävendahl L, Chagin A (2019) A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate Nature, 567 (7747): 234-238
o	Baert L, Benkhoucha M, Popa N, Ahmed M, Manfroi B, Boutonnat J, Sturm N, Raguenez G, Tessier M, Casez O, Marignier R, Ahmadi M, Broisat A, Ghezzi C, Rivat C, Sonrier C, Hahne M, Baeten D, Vives R, Lortat-Jacob H, Marche P, Schneider P, Lassmann H, Boucraut J, Lalive P, Huard B (2019) APRIL-mediated anti-inflammatory response of astrocytes in multiple sclerosis Ann Neurol, 85(3): 406-420
o	Gross C, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher A, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud D, Loussouarn D, Parratt J, Barnett M, Buckland M, Hardy T, Reddel S, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth S, Martin-Blondel G, Wiendl H, Liblau R (2019) CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome Nat Commun, 10 (1): 5779
o	Hillebrand S, Schanda K, Nigritinou M, Tsymala I, Böhm D, Peschl P, Takai Y, Fujihara K, Nakashima I, Misu T, Reindl M, Lassmann H, Bradl M (2019) Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat Acta Neuropathol, 137(3): 467-485
o	Konjevic Sabolek M, Held K, Beltrán E, Niedl A, Meinl E, Hohlfeld R, Lassmann H, Dornmair K (2019) Communication of CD 8 + T cells with mononuclear phagocytes in multiple sclerosis Ann Clin Transl Neurol, 6(7): 1151-1164
o	Yshii L, Pignolet B, Mauré E, Pierau M, Brunner-Weinzierl M, Hartley O, Bauer J, Liblau R (2019) IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration JCI Insight, 4 (7):
o	Hernández-Torres E, Wiggermann V, Machan L, Sadovnick A, Li D, Traboulsee A, Hametner S, Rauscher A (2019) Increased mean R2* in the deep gray matter of multiple sclerosis patients: Have we been measuring atrophy? J Magn Reson Imaging, 50 (1): 201-208
o	Magliozzi R, Hametner S, Facchiano F, Marastoni D, Rossi S, Castellaro M, Poli A, Lattanzi F, Visconti A, Nicholas R, Reynolds R, Monaco S, Lassmann H, Calabrese M (2019) Iron homeostasis, complement, and coagulation cascade as CSF signature of cortical lesions in early multiple sclerosis Ann Clin Transl Neurol, 6(11): 2150-2163
o	Bergner C, Meer F, Winkler A, Wrzos C, Türkmen M, Valizada E, Fitzner D, Hametner S, Hartmann C, Pfeifenbring S, Stoltenburg‐Didinger G, Brück W, Nessler S, Stadelmann C (2019) Microglia damage precedes major myelin breakdown in X‐linked adrenoleukodystrophy and metachromatic leukodystrophy Glia, 67 (6): 1196-1209
o	Wimmer I, Scharler C, Zrzavy T, Kadowaki T, Mödlagl V, Rojc K, Tröscher A, Kitic M, Ueda S, Bradl M, Lassmann H (2019) Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis Acta Neuropathologica Communications, 7 (1): 14
o	Tröscher A, Wimmer I, Quemada-Garrido L, Köck U, Gessl D, Verberk S, Martin B, Lassmann H, Bien C, Bauer J (2019) Microglial nodules provide the environment for pathogenic T cells in human encephalitis Acta Neuropathol, 137(4): 137(4):619-635
o	Kau T, Hametner S, Endmayr V, Deistung A, Prihoda M, Haimburger E, Menard C, Haider T, Höftberger R, Robinson S, Reichenbach J, Lassmann H, Traxler H, Trattnig S, Grabner G (2019) Microvessels may Confound the “Swallow Tail Sign” in Normal Aged Midbrains: A Postmortem 7 T SW-MRI Study J Neuroimaging, 29(1): 65-69
o	Bernard-Valnet R, Cobo-Calvo A, Siegfried A, Marasescu R, Bonnan M, Ballan G, Ellie E, Bauer J, Uro-Coste E, Marignier R, Brassat D (2019) Paraneoplastic neuromyelitis optica and ovarian teratoma: A case series Mult Scler Relat Disord., 31: 97-100
o	Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller W, Lassmann H, Engelhardt B (2019) PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation Front Immunol, 10: 711
o	Zrzavy T, Höftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, Lassmann H (2019) Pro-inflammatory Activation of Microglia in the Brain of Patients with Sepsis Neuropathol Appl Neurobiol, 45(3): 278-290
o	Prakash V, Carson B, Feenstra J, Dass R, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks M, Kurylo C, Batchelder J, Haller K, Hashimoto A, Rundqivst H, Condeelis J, Allis C, Drygin D, Nieto M, Andäng M, Percipalle P, Bergh J, Adameyko I, Farrants A, Hartman J, Lyden D, Pietras K, Blanchard S, Vincent C (2019) Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease Nat Commun, 10 (1):
o	Anaby D, Morozov D, Seroussi I, Hametner S, Sochen N, Cohen Y (2019) Single‐ and double‐Diffusion encoding MRI for studying ex vivo apparent axon diameter distribution in spinal cord white matter NMR Biomed, 32 (12): e4170
o	Soldatov R, Kaucka M, Kastriti M, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino M, Boismoreau F, Hilscher M, Yokota C, Qian X, Nilsson M, Bronner M, Croci L, Hsiao W, Guertin D, Brunet J, Consalez G, Ernfors P, Fried K, Kharchenko P, Adameyko I (2019) Spatiotemporal structure of cell fate decisions in murine neural crest Science, 364 (6444): eaas9536
o	Haindl M, Köck U, Zeitelhofer-Adzemovic M, Fazekas F, Hochmeister S (2019) The formation of a glial scar does not prohibit remyelination in an animal model of multiple sclerosis Glia, 67 (3): 467-481
2019 Reviews
o	Lassmann H (2019) Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis Front Immunol, 9: 3116
o	Titulaer M, Irani S, Lassmann H (2019) PDE10A antibodies in autoimmune encephalitis Neurology, 93(8): 327-328
o	Ciccarelli O, Cohen J, Reingold S, Weinshenker B, Amato M, Banwell B, Barkhof F, Bebo B, Becher B, Bethoux F, Brandt A, Brownlee W, Calabresi P, Chatway J, Chien C, Chitnis T, Ciccarelli O, Cohen J, Comi G, Correale J, De Sèze J, De Stefano N, Fazekas F, Flanagan E, Freedman M, Fujihara K, Galetta S, Goldman M, Greenberg B, Hartung H, Hemmer B, Henning A, Izbudak I, Kappos L, Lassmann H, Laule C, Levy M, Lublin F, Lucchinetti C, Lukas C, Marrie R, Miller A, Miller D, Montalban X, Mowry E, Ourselin S, Paul F, Pelletier D, Ranjeva J, Reich D, Reingold S, Rocca M, Rovira A, Schlaerger R, Soelberg Sorensen P, Sormani M, Stuve O, Thompson A, Tintoré M, Traboulsee A, Trapp B, Trojano M, Uitdehaag B, Vukusic S, Waubant E, Weinshenker B, Wheeler-Kingshott C, Xu J (2019) Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders Lancet Neurol, 18 (2): 185-197
o	Lassmann H (2019) The changing concepts in the neuropathology of acquired demyelinating central nervous system disorders. Curr Opin Neurol, 32(3): 313-319
o	Zrzavy T, Kollaritsch H, Rommer P, Boxberger N, Loebermann M, Wimmer I, Winkelmann A, Zettl U (2019) Vaccination in Multiple Sclerosis: Friend or Foe? Front Immunol, 10:
2018 Original Articles
o	Rubino S, Mayo L, Wimmer I, Siedler V, Brunner F, Hametner S, Madi A, Lanser A, Moreira T, Donnelly D, Cox L, Rezende R, Butovsky O, Lassmann H, Weiner H (2018) Acute microglia ablation induces neurodegeneration in the somatosensory system Nat Commun, 9 (1): 4578
o	Zrzavy T, Machado-Santos J, Christine S, Baumgartner C, Weiner H, Butovsky O, Lassmann H (2018) Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts Brain Pathol, 28(6): 791-805
o	Martin N, Molnar V, Szilagyi G, Elkjaer M, Nawrocki A, Okarmus J, Wlodarczyk A, Thygesen E, Palkovits M, Gallyas F, Larsen M, Lassmann H, Benedikz E, Owens T, Svenningsen A, Illes Z (2018) Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice Front Immunol, 9: 490
o	Weinhofer I, Zierfuss B, Hametner S, Wagner M, Popitsch N, Machacek C, Bartolini B, Zlabinger G, Ohradanova-Repic A, Stockinger H, Köhler W, Höftberger R, Regelsberger G, Forss-Petter S, Lassmann H, Berger J (2018) Impaired plasticity of macrophages in X-linked adrenoleukodystrophy Brain, 141: 2329-2342 \| Article (PDF) \|
o	Schweser F, Raffaini Duarte Martins A, Hagemeier J, Lin F, Hanspach J, Weinstock-Guttman B, Hametner S, Bergsland N, Dwyer M, Zivadinov R (2018) Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality Neuroimage, 167: 438-452
o	Blaabjerg M, Hemdrup A, Drici L, Ruprecht K, Garred P, Höftberger R, Kristensen B, Kondziella D, Sejbaek T, Hansen S, Nielsen H, Jensen P, Meyer M, Paul F, Lassmann H, Larsen M, Illes Z (2018) Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) Front Immunol, 9: 741
o	Martin N, Nawrocki A, Molnar V, Elkjaer M, Thygesen E, Palkovits M, Acs P, Sejbaek T, Nielsen H, Hegedus Z, Sellebjerg F, Molnar T, Barbosa E, Alcaraz N, Gallyas F, Svenningsen A, Baumbach J, Lassmann H, Larsen M, Illes Z (2018) Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes PlosOne, 13 (8): e0202530
o	Spadaro M, Winklmeier S, Beltrán E, Macrini C, Höftberger R, Schuh E, Thaler F, Gerdes L, Laurent S, Gerhards R, Brändle S, Dornmair K, Breithaupt C, Krumbholz M, Moser M, Kirshnamoorthy G, Kamp F, Jenne D, Hohlfeld R, Kümpfel T, Lassmann H, Kawakami N, Meinl E (2018) Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein Ann Neurol, 84(2): 315-328
o	Bagnato F, Hametner S, Franco G, Pawate S, Sriram S, Lassmann H, Gore J, Smith S, Dortch R (2018) Selective Inversion Recovery Quantitative Magnetization Transfer Brain MRI at 7T: Clinical and Postmortem Validation in Multiple Sclerosis J Neuroimaging, 28(4) : 380-388
o	Wimmer I, Tröscher A, Brunner F, Rubino S, Bien C, Weiner H, Lassmann H, Bauer J (2018) Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples Sci Rep, 8 (1): 6351
o	Kap Y, Bus-Spoor C, van Driel N, Dubbelaar M, Grit C, Kooistra S, Fagrouch Z, Verschoor E, Bauer J, Eggen B, Harmsen H, Laman J, ’t Hart B (2018) Targeted Diet Modification Reduces Multiple Sclerosis–like Disease in Adult Marmoset Monkeys from an Outbred Colony J Immunol, 201 (11): 3229-3243
o	Machado-Santos J, Saji E, Tröscher A, Paunovic M, Liblau R, Gabriely G, Bien C, Bauer J, Lassmann H (2018) The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells Brain, 141(7): 2066-2082
o	Hametner S, Endmayr V, Deistung A, Palmrich P, Prihoda M, Haimburger E, Menard C, Feng X, Haider T, Leisser M, Köck U, Kaider A, Höftberger R, Robinson S, Reichenbach JR, Lassmann H, Traxler H, Trattnig S, Grabner G. (2018) The influence of brain iron and myelin on magnetic susceptibility and effective transverse relaxation - A biochemical and histological validation study Neuroimage, 179: 117-133.
o	Reinthaler E, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill C, Hoffjan S, Epplen J, Zettl U, Hecker M, Deutschländer A, Meuth S, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick A, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A (2018) TPP2 mutation associated with sterile brain inflammation mimicking MS Neurol Genet, 4 (6): e285
o	Lemke A, Ferguson J, Gross K, Penzenstadler C, Bradl M, Mayer R, Gerner C, Redl H, Wolbank S (2018) Transplantation of human amnion prevents recurring adhesions and ameliorates fibrosis in a rat model of sciatic nerve scarring Acta Biomater, 66: 335–349
o	Bagnato F, Hametner S, Boyd E, Endmayr V, Shi Y, Ikonomidou V, Chen G, Pawate S, Lassmann H, Smith S, Welch E (2018) Untangling the R2* contrast in multiple sclerosis: A combined MRI-histology study at 7.0 Tesla PlosOne, 13 (3): e0193839
2018 Reviews
o	Hametner S, Bianco AD, Trattnig S, Lassmann H. (2018) Iron related changes in MS lesions and their validity to characterize MS lesion types and dynamics with Ultra-high field magnetic resonance imaging Brain Pathol, 28(5): 743-749
o	Bradl M, Reindl M, Lassmann H (2018) Mechanisms for lesion localization in neuromyelitis optica spectrum disorders Curr Opin Neurol, 31(3): 325-333
o	O’Loughlin E, Madore C, Lassmann H, Butovsky O (2018) Microglial Phenotypes and Functions in Multiple Sclerosis Cold Spring Harb Perspect Med., 8 (2): a028993
o	Lassmann H (2018) Multiple Sclerosis Pathology Cold Spring Harb Perspect Med., 8(3): a028936
o	Lassmann H (2018) Multiple Sclerosis Pathology and its Reflection by Imaging Technologies: Introduction Brain Pathol, 28 (5): 721-722
o	Wimmer I, Zrzavy T, Lassmann H (2018) Neuroinflammatory responses in experimental and human stroke lesions J Neuroimmunol, 323: 10-18
2017 Original Articles
o	Lemke A, Penzenstadler C, Ferguson J, Lidinsky D, Hopf R, Bradl M, Redl H, Wolbank S, Hausner T (2017) A novel experimental rat model of peripheral nerve scarring: reliably mimicking post-surgical complications and recurring adhesions Dis Model Mech, 10(8): 1015-1025
o	Körtvélyessy P, Breu M, Pawlitzki M, Metz I, Heinze H, Matzke M, Mawrin C, Rommer P, Kovacs G, Mitter C, Reindl M, Brück W, Wandinger K, Lassmann H, Höftberger R, Leypoldt F (2017) ADEM-like presentation, anti-MOG antibodies, and MS pathology: TWO case reports Neurol Neuroimmunol Neuroinfl, 4 (3): e335
o	Espitia Pinzon N, Sanz-Morello B, Brevé J, Bol J, Drukarch B, Bauer J, Baron W, van Dam A (2017) Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination Sci Rep, 7: 40995
o	Gebauer C, Pignolet B, Yshii L, Mauré E, Bauer J, Liblau R (2017) CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model Oncoimmunology, 6 (2): e1260212
o	Michailidou I, Naessens D, Hametner S, Guldenaar W, Kooi E, Geurts J, Baas F, Lassmann H, Ramaglia V (2017) Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis Glia, 65(2): 264-277
o	Laukoter S, Rauschka H, Tröscher A, Köck U, Saji E, Jellinger K, Lassmann H, Bauer J (2017) Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis Acta Neuropathol, 133(4): 613-627
o	Petersen M, Ryu J, Chang K, Etxeberria A, Bardehle S, Mendiola A, Kamau-Devers W, Fancy S, Thor A, Bushong E, Baeza-Raja B, Syme C, Wu M, Rios Coronado P, Meyer-Franke A, Yahn S, Pous L, Lee J, Schachtrup C, Lassmann H, Huang E, Han M, Absinta M, Reich D, Ellisman M, Rowitch D, Chan J, Akassoglou K (2017) Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage Neuron, 96(5): 1003-1012
o	Peschl P, Schanda K, Zeka B, Given K, Böhm D, Ruprecht K, Saiz A, Lutterotti A, Rostásy K, Höftberger R, Berger T, Macklin W, Lassmann H, Bradl M, Bennett J, Reindl M (2017) Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination J Neuroinflammation, 14 (1): 208
o	Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner H, Lassmann H (2017) Loss of ‘homeostatic’ microglia and patterns of their activation in active multiple sclerosis Brain, 140 (7): 1900-1913
o	Furlan A, Dyachuk V, Kastriti M, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko P, Ernfors P, Adameyko I (2017) Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla Science, 357 (6346): eaal3753
o	Kitic M, Karram K, Israel N, Yogev N, Lacher S, Tang Y, Yigit H, Bauer J, Wanke F, Knezovic A, Trotter J, Kurschus F, Waisman A (2017) NG2 plays a role in neuroinflammation but is not expressed by immune cells Acta Neuropathol, 134 (2): 325-327
o	Dunham J, Bauer J, Campbell G, Mahad D, van Driel N, van der Pol S, ‘t Hart B, Lassmann H, Laman J, van Horssen J, Kap Y (2017) Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis J Neuropath Exp Neurol, 76(6): 467-478
o	Popescu B, Frischer J, Webb S, Tham M, Adiele R, Robinson C, Fitz-Gibbon P, Weigand S, Metz I, Nehzati S, George G, Pickering I, Brück W, Hametner S, Lassmann H, Parisi J, Yong G, Lucchinetti C (2017) Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions Acta Neuropathol, 134 (1): 45-64
o	Popkirov S, Ayzenberg I, Hahn S, Bauer J, Denno Y, Rieckhoff N, Radzimski C, Hans V, Berg S, Roghmann F, Noldus J, Bien C, Skodda S, Wellmer J, Stöcker W, Krogias C, Gold R, Schlegel U, Probst C, Komorowski L, Miske R, Kleiter I (2017) Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis Acta Neuropathologica Communications, 5 (1): \| Supplement \|
o	Tröscher A, Klang A, French M, Quemada-Garrido L, Kneissl S, Bien C, Pákozdy A, Bauer J (2017) Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies Front Immunol, 8: 1364
o	Dunham J, van de Vis R, Bauer J, Wubben J, van Driel N, Laman J, ‘t Hart B, Kap Y (2017) Severe oxidative stress in an acute inflammatory demyelinating model in the rhesus monkey PlosOne, 12 (11): e0188013
o	Dal-Bianco A, Grabner G, Kronnerwetter C, Weber M, Höftberger R, Berger T, Auff E, Leutmezer F, Trattnig S, Lassmann H, Bagnato F, Hametner S (2017) Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging Acta Neuropathol, 133 (1): 25-42
o	Wiggermann V, Hametner S, Hernández-Torres E, Kames C, Endmayr V, Kasprian G, Höftberger R, Li D, Traboulsee A, Rauscher A (2017) Susceptibility-sensitive MRI of multiple sclerosis lesions and the impact of normal-appearing white matter changes NMR Biomed, 30 (8): e3727
o	Gabriely G, da Cunha A, Rezende R, Kenyon B, Madi A, Vandeventer T, Skillin N, Rubino S, Garo L, Mazzola M, Kolypetri P, Lanser A, Moreira T, Faria A, Lassmann H, Kuchroo V, Murugaiyan G, Weiner H (2017) Targeting latency-associated peptide promotes antitumor immunity Sci Immunol, 2 (11): eaaj1738
o	Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O’Loughlin E, Xu Y, Fanek Z, Greco D, Smith S, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich J, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner F, Litvak V, Holtzman D, Lassmann H, Weiner H, Ochando J, Haass C, Butovsky O (2017) The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases Immunity, 47 (3): 566-581.e9
o	Karamita M, Barnum C, Möbius W, Tansey M, Szymkowski D, Lassmann H, Probert L (2017) Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia JCI Inside, 2 (8): e87455
2017 Reviews
o	’t Hart B, Dunham J, Faber B, Laman J, van Horssen J, Bauer J, Kap Y (2017) A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model Front Immunol, 8: 804-
o	Kuhlmann T, Ludwin S, Prat A, Antel J, Brück W, Lassmann H. (2017) An updated histological classification system for multiple sclerosis lesions Acta Neuropathol, 133(1): 13-24
o	Bauer J, Becker A, Elyaman W, Peltola J, Rüegg S, Titulaer M, Varley J, Beghi E (2017) Innate and adaptive immunity in human epilepsies Epilepsia, 58: 57-68
o	Zeka B., Lassmann H., Bradl M. (2017) Müller cells and retinal axons can be primary targets in experimental neuromyelitis optica spectrum disorder Clinical and Experimental Neuroimmunology, 8: 3-7
o	Lassmann H, Bradl M. (2017) Multiple sclerosis: experimental models and reality Acta Neuropathol, 133(2): 223-244
o	Peschl P, Bradl M, Höftberger R, Berger T, Reindl M (2017) Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases Front Immunol, 8: 529
o	Kawachi I, Lassmann H (2017) Neurodegeneration in multiple sclerosis and neuromyelitis optica J Neurol Neurosurg Psychiatry, 88(2):: 137-145
o	Türkoğlu R, Lassmann H, Aker F, Tzartos J, Tzartos S, Tüzün E (2017) Recurrent tumefactive demyelinating lesions: a pathological study Clin Neuropathol, 36(4): 195-198
o	Lassmann H (2017) Targets of therapy in progressive MS Mult Scler, 23 (12): 1593-1599
o	Zurawski J, Lassmann H, Bakshi R. (2017) Use of Magnetic Resonance Imaging to Visualize Leptomeningeal Inflammation in Patients With Multiple Sclerosis: A Review. Jama Neurol, 74(1): 100-109
2017 Book Chapters
o	Finsterer, J; Pakozdy, A; Bradl, M (2017) Epilepsy in Humans and Animals: From Patients to Disease Models. In: Jensen-Jarolim, E. (Eds.), Comparative Medicine: disorders linking humans with their animals Springer-Verlag : 13-25
o	Höftberger R, Lassmann H (2017) Immune-mediated disorders. In: (Eds.), Handbook of Clinical Neurology : 285-299
o	Höftberger R, Lassmann H (2017) Inflammatory demyelinating diseases of the central nervous system. In: (Eds.), Handbook of Clinical Neurology : 263-283
2016 Original Articles
o	Ramadan A, Lucca L, Carrié N, Desbois S, Axisa P, Hayder M, Bauer J, Liblau R, Mars L (2016) In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS Brain, : aww032 \| Article (PDF) \|
o	Peneder T, Bauer J, Pifl C (2016) Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice Movement Disorders, 31: 1729-1733
o	Zeka B, Hastermann M, Kaufmann N, Schanda K, Pende M, Misu T, Rommer P, Fujihara K, Nakashima I, Dahle C, Leutmezer F, Reindl M, Lassmann H, Bradl M (2016) Aquaporin 4-specific T cells and NMO-IgG cause primary retinal damage in experimental NMO/SD Acta Neuropathologica Communications, 4 (1): 82
o	Dunham J, Lee L, van Driel N, Laman J, Ni I, Zhai W, Tu G, Lin J, Bauer J, ‘t Hart B, Kap Y (2016) Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis J Neuroimmune Pharmacol, 11 (1): 73-83
o	Bernard-Valnet R, Yshii L, Quériault C, Nguyen X, Arthaud S, Rodrigues M, Canivet A, Morel A, Matthys A, Bauer J, Pignolet B, Dauvilliers Y, Peyron C, Liblau R (2016) CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice PNAS, 113 (39): 10956-10961
o	Yshii L, Gebauer C, Pignolet B, Mauré E, Quériault C, Pierau M, Saito H, Suzuki N, Brunner-Weinzierl M, Bauer J, Liblau R (2016) CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model Brain, 139 (11): 2923-2934
o	Oji S, Nicolussi E, Kaufmann N, Zeka B, Schanda K, Fujihara K, Illes Z, Dahle C, Reindl M, Lassmann H, Bradl M (2016) Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord PLoS One, 11 (3): e0151244
o	Burm S, Peferoen L, Zuiderwijk-Sick E, Haanstra K, ‘t Hart B, van der Valk P, Amor S, Bauer J, Bajramovic J (2016) Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself J Neuroinflammation, 13 (1):
o	Schuh E, Berer K, Mulazzani M, Feil K, Meinl I, Lahm H, Krane M, Lange R, Pfannes K, Subklewe M, Gurkov R, Bradl M, Hohlfeld R, Kumpfel T, Meinl E, Krumbholz M (2016) Features of Human CD3+CD20+ T Cells J Immunol, 197 (4): 1111-1117
o	Wiedermann U, Sitte HH, Burgmann H, Eser A, Falb P, Holzmann H, Kitchen M, Köller M, Kollaritsch H, Kundi M, Lassmann H, Mutz I, Pickl WF, Riedl E, Sibilia M, Thalhammer F, Tucek B, Zenz W, Zwiauer K. (2016) Guidelines for vaccination of immunocompromised individuals Wiener Klinische Wochenschrift, 128 (S4): 337-376
o	Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL (2016) IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation Brain, 139 (7): 1939-1957
o	Adzemovic M, Zeitelhofer M, Leisser M, Köck U, Kury A, Olsson T (2016) Immunohistochemical Analysis in the Rat Central Nervous System and Peripheral Lymph Node Tissue Sections J Vis Exp, (117):
o	Allan D, Fairlie-Clarke K, Elliott C, Schuh C, Barnett S, Lassmann H, Linnington C, Jiang H (2016) Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system Acta Neuropathologica Communications, 4 (1): 75
o	Haider L, Zrzavy T, Hametner S, Höftberger R, Bagnato F, Grabner G, Trattnig S, Pfeifenbring S, Brück W, Lassmann H (2016) The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain Brain, 139 (3): 807-815
o	Alidzanovic L, Starlinger P, Schauer D, Maier T, Feldman A, Buchberger E, Stift J, Koeck U, Pop L, Gruenberger B, Gruenberger T, Brostjan C (2016) The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a host-blockade of VEGF clearance Oncotarget, 7(35): 57197-57212
o	Blaabjerg M, Ruprecht K, Sinnecker T, Kondziella D, Niendorf T, Kerrn-Jespersen B, Lindelof M, Lassmann H, Kristensen B, Paul F, Illes Z (2016) Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI Neurol Neuroimmunol Neuroinflamm, 3 (3): e226-e226
2016 Reviews
o	Martin-Blondel G, Brassat D, Bauer J, Lassmann H, Liblau R (2016) CCR5 blockade for neuroinflammatory diseases — beyond control of HIV Nat Rev Neurol, 12(2): 95-105
o	Lassmann H (2016) Demyelination and Neurodegeneration in Multiple Sclerosis: The Role of Hypoxia Ann Neurol, 79 (4): 520-521
o	Bauer J, Lassmann H. (2016) Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis Methods Mol Biol, 1304: 211-229
o	Lassmann H, van Horssen J. (2016) Oxidative stress and its impact on neurons and glia in multiple sclerosis lesions Biochim Biophys Acta, 1862(3): 506-510
o	Valent P, Groner B, Schumacher U, Superti-Furga G, Busslinger M, Kralovics R, Zielinski C, Penninger J, Kerjaschki D, Stingl G, Smolen J, Valenta R, Lassmann H, Kovar H, Jäger U, Kornek G, Müller M, Sörgel F (2016) Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine J Innate Immun, 8(2): 111-120
2016 Book Chapters
o	Bradl M, Lassmann H (2016) Neurologic autoimmunity mechanisms revealed by animal models. In: (Eds.), Handbook of Clinical Neurology : 121-143
o	Bauer J, Bien C (2016) Neuropathology of autoimmune encephalitides. In: (Eds.), Handbook of Clinical Neurology : 107-120